The 
previous the year was a complete disaster for the Diamondbacks losing 98-games, the second most in franchise history. As a result the Diamondbacks fired their manager replacing him with Chip Hale.
On April 6, 2015 the Diamondbacks hosted the San Francisco Giants at Chase Field in Phoenix AZ.
Right-handed pitcher Josh Collmenter would make his first Opening Day start taking the mound for the Arizona Diamondbacks.
The Opening Day line-up featured four changes from the previous season and several position changes.
Chris Owings would get his second Opening Day start this year at second base. Mark Trumbo made his second Opening Day start this year in right field. Aaron Hill started at third base after playing second base in last year's opening game. A.J. Pollock played center field in his third consecutive game and Paul Goldschmidt played first base for the fourth consecutive year. Collmenter was the Opening Day starting pitcher for the first time in his career.
Besides Collmenter, the new Opening Day starters were Ender Inciarte who started in left field, Tuffy Gosewisch who started at catcher, and Nick Ahmed who was the starting shortstop in his young career.
For the eighth time in franchise history the Diamondbacks lost their season opener. The final score Diamondbacks 4 - Giants 5 in front of 49,093.
| 2015 | ||
| Order | Name | Position |
| 1. | A.J. Pollock | CF |
| 2. | Ender Inciarte | LF |
| 3. | Paul Goldschmidt | 1B |
| 4. | Mark Trumbo | RF |
| 5. | Aaron Hill | 3B |
| 6. | Chris Owings | 2B |
| 7. | Tuffy Gosewisch | C |
| 8. | Nick Ahmed | SS |
| 9. | Josh Collmenter | RHP |
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